hrp0082p3-d2-683 | Bone (1) | ESPE2014

Two Different Diagnosis of Pseudohypoaldosteronism

Bulus Derya , Andiran Nesibe , Colakoglu Elif Yagli , Altuntas Nilgun

Background: Pseudohypoaldosteronism (PHA) is a disorder caused by aldosterone resistance with impaired sodium reabsorption and potassium excretion from the body. PHA is subdivided into primary (genetic) and secondary (transient) forms. Primary PHA is caused by mutations in genes encoding epithelial sodium channel or mineralocorticoid receptors. The secondary PHA may occur due to urinary tract malformations, urinary tract infections (UTI), drugs, etc. We present here two cases ...

hrp0082p2-d1-537 | Puberty and Neuroendocrinology | ESPE2014

The Evaluation of Possible Role of Endocrine Disrupters in Precocious Puberty

Bulus Derya , Asci Ali , Andiran Nesibe , Kocer-Gumusel Belma , Colakoglu Elif Yagli

Background: Human health might be negatively affected by chemicals named as endocrine disrupters. Researchers showed that phthalates (bis-(2-ethylhexyl) phthalate (DEHP), mono-(2-ethylhexyl) phthalate (MEHP)) and bisphenol A (BPA) have an anti-androgenic and/or estrogenic effects. These endocrine disruptors are accused in occurrence and/or possible increase in unusual early puberty in girls in recent years.Objective and hypotheses: The aim of th...